PSGL-1 decorated with sialyl Lewisa/x promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement
Abstract Dissemination of multiple myeloma into the bone marrow proceeds through sequential steps mediated by a variety of adhesion molecules and chemokines that eventually results in the extravasation Skin Care Oils of malignant plasma cells into this protective niche.Selectins are a class of C-type lectins that recognize carbohydrate structures e